International Society of Sports Nutrition position stand: creatine supplementation and exercise
One of the most studied nutrients in sports science. The review confirms creatine monohydrate supports muscle energy and training adaptation, with a strong safety record.
An independent summary of published ingredient research, not the original paper or a clinical study of CORE49.
What the research found
This position stand brings together the creatine literature rather than reporting one new experiment. It describes increases in muscle creatine stores and improvements in high-intensity exercise performance and training adaptation.
The important context
The strongest exercise evidence concerns supplementation alongside training. The review spans different populations, doses and outcomes; it does not establish that every product containing creatine produces the same effect.
Where CORE49 fits
This paper informs our understanding of an individual ingredient. It did not evaluate the finished CORE49 formula. Study populations, ingredient forms and amounts can differ from those in our daily drink; ingredient evidence and formula evidence are not interchangeable.
